– Detecting cell genetics for diagnosis in pregnancy by using Beadchip array
– Screening abnormal number of chromosomes (chromosome 13, 18, 21, X, Y) from an embryo biopsy – week 10 embryos in cases of natural pregnancy, week 8 in case of In vitro fertilization (IVF)
– Whole human genome sequencing, small whole-genome sequencing, whole exome sequencing
– Whole genome resequencing
– Transcriptome sequencing
– Gene expression analysis
– Targeted sequencing
– Denovo sequencing
– mRNA sequencing, small RNA sequencing
– Mitochondrial DNA sequencing in forensic applications
– Applied in parental determination, forensic sciences
– HLA genotyping applied for organ transplantation
– Sequencing to detect clearly gene mutations in cancer diagnosis and targeted treatment
– Maximum Output: 16-120 Gb per run, suitable for various applications
– Data quality: Quality Score > Q30
– Sequencing the whole human genome with the deep coverage of 30X in one run
– Maximum sequencing: 16 exomes, 20 transcriptomes, 40 gene expression profiles in one run
– Fully automated process:
- NIPT solution, sequencing DNA extracted from maternal blood and generating results within 48 hours
- The normal procedure from sample to data is the rapidest, within 30 hours
Microarray function of the NextSeq 550 system:
- SNP chips are suitable for:
- Infinium Human CytoSNP-12 BeadChip: each BeadChip is scanned in 40 minutes, each sample is scanned in 3.3 minutes
- Infinium CytoSNP-850k BeadChip: each BeadChip is scanned in 40 minutes, each sample is scanned in 5 minutes
- Infinium HumanKaryomap-12 BeadChip: each BeadChip is scanned in 40 minutes, each sample is scanned in 3.3 minutes
See more at: https://sapac.illumina.com/systems/sequencing-platforms/nextseq.html
