Model: NextSeq 550
Manufacturer: Illumina / USA
– The NextSeq 550 System is the only bifunctional system: next-generation sequencing and Beadchip Microarray (BeadArray)
– Next-Generation Sequencing System uses sequencing technology: Sequencing by Synthesis – SBS
– The whole process of sequencing is carried out on the surface of flow cells, convenient and easy handling.

– Detecting cell genetics for diagnosis in pregnancy by using Beadchip array
– Screening abnormal number of chromosomes (chromosome 13, 18, 21, X, Y) from an embryo biopsy – week 10 embryos in cases of natural pregnancy, week 8 in case of In vitro fertilization (IVF)
– Whole human genome sequencing, small whole-genome sequencing, whole exome sequencing
– Whole genome resequencing
– Transcriptome sequencing
– Gene expression analysis
– Targeted sequencing
– Denovo sequencing
– mRNA sequencing, small RNA sequencing
– Mitochondrial DNA sequencing in forensic applications
– Applied in parental determination, forensic sciences
– HLA genotyping applied for organ transplantation
– Sequencing to detect clearly gene mutations in cancer diagnosis and targeted treatment

– Maximum Output: 16-120 Gb per run, suitable for various applications
– Data quality: Quality Score > Q30
– Sequencing the whole human genome with the deep coverage of 30X in one run
– Maximum sequencing: 16 exomes, 20 transcriptomes, 40 gene expression profiles in one run
– Fully automated process:

  • NIPT solution, sequencing DNA extracted from maternal blood and generating results within 48 hours
  • The normal procedure from sample to data is the rapidest, within 30 hours

Microarray function of the NextSeq 550 system:

  • SNP chips are suitable for:
  • Infinium Human CytoSNP-12 BeadChip: each BeadChip is scanned in 40 minutes, each sample is scanned in 3.3 minutes
  • Infinium CytoSNP-850k BeadChip: each BeadChip is scanned in 40 minutes, each sample is scanned in 5 minutes
  • Infinium HumanKaryomap-12 BeadChip: each BeadChip is scanned in 40 minutes, each sample is scanned in 3.3 minutes

See more at: https://sapac.illumina.com/systems/sequencing-platforms/nextseq.html

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